Alstrom Syndrome causes childhood blindness, hearing loss, heart failure, kidney failure, diabetes type two, obesity and many related health problems. Alstrom Syndrome UK (ASUK) is a small family run charity providing support and advice to families living with Alstrom Syndrome. We provide newsletters an annual family conference and quarterly clinic support.

The British Council for the Prevention of Blindness prevents blindness worldwide by funding research into the causes of blindness and more effective treatments. The charity also specialises in training for medical professionals from developing countries who learn how to set up programmes which save the sight of many thousands of people.

It aims to improve the understanding of Porphyria, by reaching out to patients, relatives, doctors and medical staff, etc. Early diagnosis is vital if we are to improve the quality of life for those affected by it. It also provides a social support system for sufferers and their families

British Scoliosis Research Foundation is the only charity that exists solely to promote research into the treatment of spinal deformities. The BSRF works closely with the Scoliosis Association UK and the British Scoliosis Society. It funds research into scoliosis and holds an international symposium to spread the knowledge gained from research.

It funds ethical original non-animal tested research into the causes, early diagnosis, treatment, cure and prevention of Cancer. It also supports Cancer sufferers with amenities to improve their quality of life

It helps people with a SCI regain independance by providing grants for equipment or rehabilitation and much needed advice and support to their families and carers.

The Trust raises funds in memory of Ciaran, who suffered from a genetic skin disorder called Keratitis-Ichthyosis-Deafness Syndrome (?KID syndrome?). The Trust aims to help people with similar conditions, as well as supporting research and promoting awareness about the difficulties of living with the multiple disabilities of blindness, deafness and skin disorders.

Established by Clarke’s parents in 1996 when 10-year old Clarke Lister died suddenly of a brain haemorrhage. We promote and assist research into causes and treatment of brain haemorrhage and share the useful results for public benefit, as well as providing support services for families affected by brain haemorrhage

Deafax works to empower deaf people of all ages to lead fulfilling lives through the use of innovative communications technologies and by developing deaf-friendly resources and delivering training and workshops. By making information more accessible, visual and interactive Deafax supports deaf people, enabling them to reach their full potential.

funds research into stammering,particularly research with practical outcomes.supports training of practitioners to enable sharing of good practice.

Two babies are born every day with Down's syndrome. Through information and support for people with Down's syndrome, their families and professionals, the Down's Syndrome Association helps these people live full and rewarding lives.

Is a national charity formed by parents of Down Syndrome children and adults who wanted a greater emphasis placed on medical research in order to alieviate the problems caused by learning difficulties and to relieve and reduce the associated health complications caused by illnesses like early onset Alzheimer’s disease and dementia

The DMD Trust raises funds for research into cures for Duchenne & Becker Muscular Dystrophy. Duchenne is the UK's second most common inherited life-threatening disease.

The DMD Trust raises funds for research into cures for Duchenne & Becker Muscular Dystrophy. Duchenne is the UK's second most common inherited life-threatening disease.

Free children?s clinics for the diagnosis and treatment of reading difficulties. Provides accurate and unbiased information on latest research to educational/health professionals, media and general public in UK and internationally. Supports academic researchers ? developing the skills and knowledge needed to continue scientific advance in the study of dyslexia.

Based in Plymouth, the study aims to unravel the factors that lead to diabetes and its complications. The seeds of diabetes are sown in childhood, and the charity's mission - Stop diabetes in childhood - declares the need to act early if the epidemic of diabetes is to be prevented.

The Ethan Perkins Trust provides grants for children with brain tumours, within Wales. The Trust donates funds to childhood glioma research projects. Named after 11 year old Ethan, who fought a brave 8 month battle against dipg. .

Fanconi Hope is a charity set up to sponsor research and support families affected by the rare genetic disorder Fanconi Anaemia that affects young children, leading to bone marrow failure and bone marrow transplantation, with very high subsequent risk of leukaemia and head & neck cancers.

The GM Trust was established in 2007, after Gavriel was diagnosed with Duchenne Muscular Dystrophy when he was 4 years old. DMD is a degenerative and as yet, incurable muscle wasting disease. which boasts a tragic 100% fatality rate. The objective of the trust is to promote research into the treatment, cure, care and welfare of those people suffering from DMD. Funding is urgently required in order to increase the speed and quantity of research currently being undertaken.

Since 1985, the GBS Support Group has supported those affected by the neuropathies Guillain-Barré syndrome and CIDP, and their clinical variants. The Charity provides information and support to sufferers and their families and aims to raise awareness of the illnesses amongst both medical professionals and the general public. It raises funds for cutting-edge research into the illnesses.

Headfirst exists to raise funds to support research into acute conditions of the nervous system which result in mental and physical disability. These could be due to a stroke, brain tumour, sudden brain haemorrage or to a serious head injury.

National charity which supports and promotes the interests of adults living with acquired hearing loss (AHL) and their families. It provides information and advice, training and research and works with volunteers to raise awareness of the needs of people with AHL. Specialised rehabilitation, personal development and communication courses support people at all stages of AHL.

The Institute of Orthopaedics, the research and teaching unit of the Robert Jones and Agnes Hunt Orthopaedic Hospital at Oswestry, Shropshire has a national and international reputation and is very much regarded as a Centre of Excellence. The 2010 Virgin London Marathon will have 37 runners supporting the Institute and funds will be raised for medical research at the hospital which will be utilised to fund innovative research projects. Raising funds in the present economic climate is exceptionally difficult and all monies received will be much appreciated.

ICOD Ltd is a user-led organisation of disabled people, providing a range of services including information and advice, awareness training, access auditing and running Inverclyde Shopmobility. We also campaign locally and nationally on issues affecting disabled people.

Kingwood provides support to people with autism. It's vision is that adults with autism will be valued by and contribute to society.

We help amputees in the North East of Scotland i.e. one of our Members, Kelly Cumming, who lost her leg due to cancer at the age of 16, needs sponsorship for running the New York Marathon where she hopes to raise funds for Bone Cancer Research. She firstly requires a new running limb from Dorset Orthopaedics for this challenge.

The Lord Mayor, Councillor Michael Wilkes, has chosen four charities to benefit from his charity appeal ? The Birmingham Fund for Pancreatic Cancer Research, a fund set up to raise funds for research, conducted in Birmingham, to improve diagnostic methods and improve the survival rate of 3% after 5 years which has not changed in four decades, St Basil?s who do outstanding work with young people to tackle and prevent homelessness and its consequences, WAITS (Women Acting in Today?s Society) an organisation doing outstanding work enabling women in all communities to overcome barriers and play their full role in society, and Lord Mayor?s Engineering Scholarships, a fund set up to support the study and practice of engineering in Birmingham encouraging and enabling young people from Birmingham to take up engineering both as a course of study and as a fulfilling future career. Further details on the charities and fundraising activities can be found at :- http://www.birmingham.gov.uk/lord-mayor-charity

The ME Association is a campaigning national charity which provides information and support to 240.000 people in the UK with ME/Chronic Fatigue Syndrome, their families and carers, through a quarterly magazine, literature, education and training. It also funds biomedical research through The MEA Ramsay Research Fund and runs the ME Connect helpline.

Middlesbrough MS Therapy Centre is an independant local charity that provides a unique service of therapies and support to MS sufferers their families and carers.

Moebius Syndrome is a rare congenital disorder which to date, has no cure. It affects primarily the 6th & 7th cranial nerves, which means that those with the condition are unable to move their faces (can't smile, frown, suck, grimace or blink eyes). We aim to raise £250,000 to fund research into the cause of Moebius.

The Muir Maxwell Trust is the UK's only charity dedicated to paediatric epilepsy. The Trust?s remit is to provide practical support to children and their families coping with severe epilepsy and to increase awareness and understanding of epilepsy and help remove the stigma associated with the condition.

The Multiple Sclerosis Resource Centre (MSRC) is a proactive and innovative charity passionately committed to supporting anyone affected by Multiple Sclerosis through access to unbiased information and advice. Our approach is to encourage individuals to make choices that are appropriate to their daily lives, empowering them to maximise their potential.

Some of the services MSRC provides include:

* A 24 hour, freephone Telephone Counselling Service available 365 days a year * An advisory service with access to MS Specialist Advisors and a Welfare Rights and Benefits Advisor * Publish the renowned MS journal, New Pathways * Maintain a comprehensive website, updated daily and providing a lively online community through its forums and chat rooms

MSRC strongly believes that "Life is for Living" and by providing unbiased information and advice, people affected by MS can make choices that are relevant to their particular needs.

The MS Society of Great Britain & Northern Ireland is the UK's largest organisation dedicated to supporting the 100,000 people, their families and carers affected by multiple sclerosis.

The Muscular Dystrophy Campaign leads the fight against muscle disease.

We provide free care and support for babies, children and adults affected by muscle disease and fund world-class research to find treatments and cures, provide grants towards equipment and campaign to raise awareness and bring about change.

also known as Yorkshire Eye Research, is a Branch of the National Eye Research Centre, which raises money to spend on eye research in Yorkshire. This research is not funded by the NHS. Please be generous.

The Neuropathy Trust is committed to a better future for all sufferers of peripheral neuropathy and neuropathic pain. Through education and communication to patients and healthcare professionals, the aim of the Trust is to raise awareness of these neuropathic disorders and provide a lifeline to all sufferers.

Support Newcastle University's world leading medical research teams who are dedicated to tackling critical health issues.

Our key areas of focus include ageing, stem cells, cancer, cell biology, genetics, drug development, medicine in society, and neuroscience. Newcastle's Faculty of Medical Sciences supports strong basic science that translates to clinical research for the benefit of patients by encouraging collaborative working on specific diseases between scientists and clinicians across disciplines and specialties.

We are indebted to our supporters who, through their enthusiastic charitable support, have helped us to take forward research and teaching that is now among the best in the world.

The charity focuses on raising money to fund scientists who are researching a cure for spinal chord injury. To date we have raised funds through the sale of a cookbook, 'Off Duty', fundraising dinners and sponsorship events. Thank you for your support.

The Nystagmus Network is a registered charity run by volunteers and one part-time employee. It relies on donations and members' subscriptions to enable us to provide support to people with the eye condition nystagmus and to promote research. It currently support several projects in the UK, covering ophthalmological research, genetics and possible drug therapies.

The Oxford Radcliffe Hospitals (ORH) Charitable Funds is the umbrella charity for over 700 funds supporting projects across the ORH NHS Trust that enhance services and facilities for patients and staff. These range from support for particular wards, at the John Radcliffe, Churchill and Horton Hospitals, to larger fundraising campaigns to support major developments such as the new Oxford Cancer Centre, the Oxford Children's Hospital, the Geratology Appeal and the Oxford Heart Centre expansion. As one of the foremost teaching trusts in the UK, the Oxford Radcliffe Hospitals enjoy a national and international reputation in fields such as cancer and cranio-facial surgery. Please give generously - your support enables us to provide the best possible healthcare in the best possible setting, to a standard far higher than the NHS alone would be able to afford.

Please note: If you wish to donate to a specific area within ORH Charitable Funds you will be able to specify this at the end of the donation process. Thank you.

The Parkinson's Appeal is a charity, which was set up by our founder Lyn Rothman to raise funds for a Deep Brain Stimulation Team headed up by the world-renowned Professor Marwan Hariz. It is through kind donations that we are able to continue our research to alleviate the soul destroying symptoms of Parkinson's disease and other neurological and movement disorders.

The charity provides information to sufferers of neurological diseases.

Remedi provides funds for medical research projects in the UK which result in new rehabilitation procedures, improved medical equipment, services and facilities which dramatically improve the quality of life for babies, children and adults and make the journey from illness or disability back to a normal life a reality.

It has over 200 members worlwide, and its aim is to provide and premote golf to individuals with Arm defects. It aims to encourage participation in golf at all levels, to increase worldwide awareness. It has helped and continues to help people with Arm defects, whether from birth or accident.

Shine Together is the charity at Frenchay and Southmead hospitals in Bristol.

Every year we raise funds in support of our patients and our staff. Thanks to your generous donations we are able to provide equipment, carry out research and deliver services to our patients that we otherwise could not afford.

Shine together is the working title for North Bristol NHS Trust Charitable Funds

Shine Together is the charity at Frenchay and Southmead hospitals in Bristol.

Every year we raise funds in support of our patients and our staff. Thanks to your generous donations we are able to provide equipment, carry out research and deliver services to our patients that we otherwise could not afford.

Shine together is the working title for North Bristol NHS Trust Charitable Funds

The Gift of Sight Appeal, established by Professor Andrew Lotery, funds world-class research into the prevention and treatment of blindness. Our principal areas of research are Age-related macular degeneration, the commonest cause of blindness in the Western world, Nystagmus and Glaucoma.

SIA is the national organisation of the UK's 40,000 spinal cord injured people. SIA provides a helpline, conducts research, campaigns and offers a peer support network, a link Scheme and a website. Promoting self-help through the sharing of experiences and advice, SIA believes that life needn't stop when you're paralysed.

Spinal Research is a pioneering charity. Its aim is to find ways to repair spinal cord injury and reverse the paralysis that results from it. Based in the UK and recognised as a leader in its field, Spinal Research funds groundbreaking projects at scientific and medical institutions around the world. The next landmark is the launch of clinical trials with paralysed volunteers. These trials will test innovative treatments that could repair damage in the human spinal cord, and so restore sensation and movement.

The Foundation`s main aim is to improve the quality of life through research. Research will be concerned with practicalities of living with spinal cord injury, but also with a committment to pushing back the scientific frontiers of spinal cord injury. One of the initial priorities is to establish a research institute adjacent to the National Spinal Injuries centre.

Thomas Pocklington Trust is the leading provider of housing, care and support services for people with sight loss in the UK. Each year Pocklington also commits around £700,000 to fund social and public health research and development projects.

The UKCNRC supports and delivers research into childhood neurological disorders across the whole UK. It links all the centres caring for children with neurological diseases together, so that coordinated national research can be delivered into these often rare and neglected conditions. Thank you for your support.

Imagine losing the ability to move and feel for the rest of your natural life. That is the reality for millions of individuals world-wide who have become victims of a paralysing spinal cord injury. Walkoncemore funds cutting edge research into a cure for this horrific condition. With your help they can weld the key to unlock paralysis.

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West Berkshire Neurological Alliance represents people in West Berkshire with a neurological condition, and those who are specifically interested in promoting the care of such people. We also support individuals who have a neurological condition for which there is no support group.

Woodlands is a unique centre providing short term respite care, utilising an holistic approach, to anyone directly affected by Multiple Sclerosis. People stay at Woodlands for a week or two to enjoy a relaxing holiday, and to enable their carers to have a break. In addition, its Resource Centre provides information support and guidance to anyone affected by MS including health and social care professionals.

To offer support to other families affected by Worster-Drought Syndrome.To raise awareness with professional workers and other interested individuals. To Support and promotion of any research into Worster-Drought Syndrome